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2017-2018学年第二学期澳门太阳城第五期学术讲座
发表时间:2018-05-02 阅读次数:602次

 

题目Massively parallel computing of the initial stage of thrombus formation

主讲Kazuyasu Sugiyama  Professor

主持: 王盛章  副教授

时间2018年5月2日(周三) 上午 10:30-11:30

地点澳门太阳城手机版邯郸路校区光华楼东主楼2601室

 

报告人简介

Prof. Kazuyasu Sugiyama received a doctor degree (Engineering) in 2000 from School of Engineering, the University of Tokyo, Japan. He was a Researcher in National Maritime Research Institute, Japan (2001-2005), a Postdoc in Physics of Fluids group, University of Twente, the Netherlands (2005-2007), and a Research Associate Professor in School of Engineering, the University of Tokyo (2008-2012). In 2012, he joined Advanced Center for Computing and Communication, RIKEN as a Unit Leader. Since April 2014, he has been working as a Professor in Graduate School of Engineering Science, Osaka University. His area of expertise is fluid dynamics and computational science with interests in multiphase flows, thermal convections, microfluidics, and biomedical applications. He received several awards including JSME Medal for Outstanding Paper (2004), Paper Award, JSMF (2014) and Frontier Award, JSME Fluids Engineering Division (2015).

 

内容简介

We have developed a multiscale simulator for the primary stage of thrombus formation as a result of a platelet adhesion to an injured vessel wall. To capture continuum scale blood flows including a large number of red blood cells (RBCs) and platelets, the simulator numerically solves fluid-structure/membrane interaction problems. It also treats a molecular scale ligand-receptor interaction between the von Willebrand factor on the injured vessel wall and the GPIb on the platelet by means of the stochastic Monte-Carlo method. From the simulated results obtained using massively parallel computing, we discuss the effect of the RBC, which induces the fluctuating motion of the surrounding liquid and causes the dispersed motion of the platelet, on the enhancement of the thrombus formation in view of the particulate flow dynamics.

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